b l o g o f p a r a g

small interference RNA

I meant to write this over a month ago. But, kept forgetting. Small interference RNAs were featured on PBS program NOVA. Check out the following website. There is a nice movie that explains how these RNA molecules work and how they are being developed as a cure.

NOVA | scienceNOW | RNAi | PBS

Here is a link to Nature journal's website that has pretty good animation about siRNAs too.

This is a very interesting technology that can be used to treat disorders at gene expression/protein production level. There are a few biotechs that are involved in developing these cures. One of them, Alnylam Pharma was bought by Novartis, recently. I bought some stock of SIRNA Therapeutics last month. They actually have a drug in Phase I trials. Hope that it will make it through and the company will be bought by a big Pharma at a premium.